I typically don't have OTPs. There is one particular pairing (Kara/Luther, from Detroit: Become Human) where I do feel weird about post-canon fics where they aren't together (or at least getting there), but I will happily accept fics where a third (or fourth, or more...) character is added into the relationship, or where the two of them are together while one or both of them is also with someone else.

Clearly, I am just very into polyamory XD